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Hany A Omar Selected Research

(1- (4- chloro- 3- nitrobenzenesulfonyl)- 1H- indol- 3- yl)- methanol

11/2013OSU-A9 inhibits angiogenesis in human umbilical vein endothelial cells via disrupting Akt-NF-κB and MAPK signaling pathways.
10/2010A novel indole-3-carbinol derivative inhibits the growth of human oral squamous cell carcinoma in vitro.
11/2009Targeting of the Akt-nuclear factor-kappa B signaling network by [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol (OSU-A9), a novel indole-3-carbinol derivative, in a mouse model of hepatocellular carcinoma.
10/2009OSU-A9, a potent indole-3-carbinol derivative, suppresses breast tumor growth by targeting the Akt-NF-kappaB pathway and stress response signaling.

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Hany A Omar Research Topics

Disease

42Neoplasms (Cancer)
09/2022 - 10/2009
12Breast Neoplasms (Breast Cancer)
09/2022 - 10/2009
9Hepatocellular Carcinoma (Hepatoma)
09/2022 - 11/2009
7Inflammation (Inflammations)
05/2021 - 04/2013
4Necrosis
07/2022 - 06/2014
2Ischemia
07/2022 - 10/2016
2Reperfusion Injury
07/2022 - 10/2016
2Lung Neoplasms (Lung Cancer)
05/2022 - 06/2021
2Carcinogenesis
06/2021 - 03/2021
2Iron Overload
05/2021 - 08/2015
2COVID-19
01/2021 - 09/2020
2Cytokine Release Syndrome
01/2021 - 09/2020
2Colitis
01/2020 - 07/2014
2Ulcer
10/2019 - 01/2015
2Stomach Ulcer (Gastric Ulcer)
01/2017 - 04/2013
1Infections
01/2022
1Leukemia
01/2022
1Liver Neoplasms (Liver Cancer)
09/2021
1Adenocarcinoma of Lung
06/2021
1Obesity
03/2021

Drug/Important Bio-Agent (IBA)

9Antineoplastic Agents (Antineoplastics)IBA
09/2021 - 06/2011
8NF-kappa B (NF-kB)IBA
05/2021 - 10/2009
7Biological ProductsIBA
01/2022 - 10/2016
6Pharmaceutical PreparationsIBA
09/2022 - 10/2016
6Caspase 3 (Caspase-3)IBA
07/2022 - 01/2018
5Proteins (Proteins, Gene)FDA Link
07/2022 - 01/2018
5Cisplatin (Platino)FDA LinkGeneric
05/2022 - 01/2016
5Sorafenib (BAY 43-9006)FDA Link
01/2022 - 01/2016
5Mitogen-Activated Protein KinasesIBA
01/2020 - 01/2014
4Biomarkers (Surrogate Marker)IBA
07/2022 - 11/2009
4CyclinsIBA
01/2018 - 01/2014
4(1- (4- chloro- 3- nitrobenzenesulfonyl)- 1H- indol- 3- yl)- methanolIBA
11/2013 - 10/2009
4indole-3-carbinolIBA
10/2010 - 10/2009
3Immune Checkpoint InhibitorsIBA
07/2022 - 01/2018
3Doxorubicin (Adriamycin)FDA LinkGeneric
05/2021 - 10/2016
3IronIBA
05/2021 - 01/2014
3tangeretinIBA
03/2021 - 01/2016
3LigandsIBA
01/2019 - 06/2014
3EnzymesIBA
01/2019 - 10/2009
3AntioxidantsIBA
01/2018 - 01/2015
3caffeic acid phenethyl esterIBA
01/2018 - 10/2016
3OSU-2SIBA
10/2017 - 06/2011
2Fingolimod Hydrochloride (FTY720)FDA Link
09/2022 - 06/2011
2Peroxidase (Myeloperoxidase)IBA
07/2022 - 01/2015
2Interleukin-6 (Interleukin 6)IBA
07/2022 - 05/2021
2Anti-Bacterial Agents (Antibiotics)IBA
01/2022 - 10/2016
2Type I DNA Topoisomerases (Topoisomerase I)IBA
11/2021 - 10/2019
2Estrogen ReceptorsIBA
10/2021 - 09/2013
2Estrogens (Estrogen)FDA Link
10/2021 - 01/2019
2ErbB Receptors (EGF Receptor)IBA
10/2021 - 07/2013
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2021 - 01/2015
2Hypoglycemic Agents (Hypoglycemics)IBA
03/2021 - 01/2020
2Phosphotransferases (Kinase)IBA
01/2021 - 01/2018
2CytokinesIBA
09/2020 - 07/2014
2pyrazoleIBA
10/2019 - 10/2017
2benzothiazoleIBA
10/2017 - 07/2013
2BenzoxazolesIBA
10/2017 - 07/2013
2Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
01/2017 - 12/2014
2Ethanol (Ethyl Alcohol)IBA
01/2015 - 04/2013
1Paclitaxel (Taxol)FDA LinkGeneric
09/2022
1vinpocetineIBA
07/2022
1Volatile Fatty AcidsIBA
07/2022
1Tumor Biomarkers (Tumor Markers)IBA
07/2022
1NADPH Oxidases (NAD(P)H oxidase)IBA
07/2022
1upadacitinibIBA
05/2022
1pyrazolanthroneIBA
01/2022
1trioctyl phosphine oxide (TOPO)IBA
01/2022
1Type II DNA Topoisomerases (Topoisomerase II)IBA
01/2022
1AlkaloidsIBA
11/2021
1belotecanIBA
11/2021
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
11/2021
1Irinotecan (Camptosar)FDA LinkGeneric
11/2021
1CamptothecinIBA
11/2021
1Topotecan (Hycamtin)FDA LinkGeneric
11/2021
1Oxidoreductases (Dehydrogenase)IBA
11/2021
1Messenger RNA (mRNA)IBA
11/2021
1Pyruvic Acid (Pyruvate)IBA
11/2021
1Progesterone Receptors (Progesterone Receptor)IBA
10/2021
1Apoptosis Regulatory ProteinsIBA
09/2021
1lupeolIBA
09/2021
1human PRMT2 proteinIBA
06/2021
1Protein-Arginine N-Methyltransferases (Methyltransferase, Protein Arginine)IBA
06/2021
1Membrane Transport Proteins (Biological Pump)IBA
05/2021
1Pentoxifylline (Trental)FDA LinkGeneric
05/2021
1ErgothioneineIBA
05/2021
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
05/2021
1Transcription Factors (Transcription Factor)IBA
05/2021
1Bortezomib (Velcade)FDA Link
05/2021
1Metformin (Glucophage)FDA LinkGeneric
03/2021
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
01/2021
1AngiotensinsIBA
01/2021
1Adrenal Cortex Hormones (Corticosteroids)IBA
09/2020
1Interleukin-6 InhibitorsIBA
09/2020
1Interleukin-1 (Interleukin 1)IBA
09/2020
1Dexamethasone (Maxidex)FDA LinkGeneric
09/2020
1DNA (Deoxyribonucleic Acid)IBA
05/2020

Therapy/Procedure

15Therapeutics
07/2022 - 10/2010
5Immunotherapy
07/2022 - 01/2018
4Drug Therapy (Chemotherapy)
09/2022 - 10/2016
1Kidney Transplantation
07/2022